ABSTRACT
Hypospadias is the second most common congenital anomaly after undescended testis worldwide. The prevalence of hypospadias in Europe stand at approximately 18.6 per 10,000 births and the number of registered cases between 2001 and 2010 in 23 EUROCAT registries is stable. Endocrine disrupting chemicals and potential EDCs can be found in various materials such as pesticides, metals, additives or contaminants in food and personal care products. Majority of studies indicate EDCs as a potential risk factor of hypospadias. According to some researches, pregnant women should avoid cosmetics with EDCs and exposure to other products containing them. However, because of incoherent experts’ opinion further valuable studies are needed to confirm this thesis.
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