ABSTRACT
The present studies discuss the 3D-AFM nano-structural features of gramicidine – A trying to
link between its nano-structural properties and its applications. The branching of polypeptide linkage
of gramicidine needs special stereo – orientation to be applied as therapeutic antibacterial cream or
ointment. The present 3D-AFM – investigations introduce important conclusive remarks enhance
scientific community to understand why gramicidin family as antibiotic cream or ointment are
structurally suitable with special surface topography enhance it to be applied as cream or ointment.
Poly-peptide linkage chains have high flexibility factor with maximum degree of freedom to be bend
or rotates.
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