The 4.0 technology revolution and the development of the digital economy have promoted e-commerce activities to increase operational efficiency at businesses. The application of management information systems and artificial intelligence to increase sales on e-commerce sites has become popular. That has become an important method in production and business activities of enterprises. The use of MIS systems, the internet to carry out online transactions: sales and marketing helps businesses save costs, improve management efficiency, as well as maximize profits. This study uses an overall approach, a change management approach to analyze, synthesize, and systematize applications and the role of management information systems and artificial intelligence to increase sales. sales on e-commerce sites. At the same time, the article also proposes solutions to apply e-commerce in business management activities, towards the formation of digital businesses.
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