The last century has been a period of extreme interest for scientific research, marked by the overcoming of the classical frontiers of scientific knowledge. Research oriented towards the infinitely small and infinitely big, in both cases beyond the borders of the visible. Quantum physics brought to a new Copernican revolution, opening the way to new questions that led to a new view of reality. At the same time, advanced theories have developed, involving every field of science, philosophy and art, rediscovering the link between unity and totality and the importance of the human potential. In a transdisciplinary approach, we consider the birth, development and important applications of quantum physics, the world of nanotechnology, pointing out on new ideas about the concepts of vacuum and entanglement, metaphysical aspects, so as the introduction of different interpretative approaches to the concept of “whole”.
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