Synthesis of thiazolylazomethine substituted pyrazole derivative using conventional and one pot multicomponent synthetic routes

ABSTRACT

Knowing the importance of thiazole and pyrazole ring systems in various useful natural products and based on the reported biological activities of the synthetic derivatives of these ring system containing compounds against different types of microbes, we have synthesized novel thiazolo – pyrazole derivatives by one pot multi component catalyst free synthetic method. The product yields have been optimized by varying the reaction parameters which includes use of different solvents and temperature. Synthesised compounds were characterised by different spectoscopic method such as ¹H NMR, IR and Mass.