Some new pyrazolo chalcone compounds were synthesized and their structure characterization was done by spectroscopic techniques such as FT-IR, 1H NMR and mass. Screenings of all these synthesized compounds were done in vitro against some bacterial and fungal strains in dimethyl sulphoxide and N,N-dimethyl formamide using agar well diffusion method. It is observed that N,N-dimethyl formamide is good solvent for these compounds in selected strains.
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