Heteroatoms like nitrogen, sulfur, and oxygen containing biologically active ethyl 4-(2,4-dichlorophenyl)-1,2,3,4-tetrahydro-6-methyl-2-thioxopyrimidine-5-carboxylate was synthesized from 2,4-dichloro benzaldehyde, acetoacetic ester and thiourea using AlTiTUD-1 as a catalyst. The synthesized compound was characterized by FT-IR, 1H and 13C NMR spectral values. The compound possesses good antimicrobial activity is determined by well diffusion method against gram positive, gram negative and fungal species. The minimum inhibitory concentration value of the compound was determined by broth dilution method.
Support the magazine and subscribe to the content
This is premium stuff. Subscribe to read the entire article.