A highly functionalized heterocyclic library were synthesized, characterized and tested for biological evaluation against bacteria and fungus. This novel synthetic rout involves nucleophilic substitution reaction of 4-chloro-2-oxo-2H-chromene-3-carbaldehyde with 4-(4-aminophenyl) morpholin-3-one in the presence of base and methanol as a solvent in good yield and high purity. All the synthesized compound of libraries characterized using 1H NMR, Mass, and IR spectroscopic technique. Also all compound screened for antimicrobial activity against standard drugs.
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