ABSTRACT
The present study was on biochemical studies on Wistar rats fed Mollusk-based protein diets compounded from Limicolaria flammea, Egeria radiata and Viviparus contectus obtained from Bayelsa State, Nigeria. Twenty-five wistar rats were used for the 28-day feeding studies and were divided into five groups of five rats each as follows: basal diet (negative control), Cerelac® (reference standard diet), L. flammea diet, E. radiata diet and V. contectus diet). All analyses were done following standard procedures. Proximate analysis of the samples showed the presence of crude protein, crude fat, carbohydrates, crude fibre and ash. The body weight change of rats in compounded diet groups were higher than the control groups. The concentration of kidney functions parameters ranged as follows: urea (3.50±0.34 mMol/l to 4.02±0.27 mMol/l), Creatinine (59.00±2.23 mMol/l to 63.00±3.39 mMol/l), sodium ion (137.80±1.79 mMol/l to 141.4±3.29 mMol/l), potassium ion (3.88±0.26 mMol/l to 4.28±0.39 mMol/l), chloride ion (93.60±1.95 mMol/l to 97.33±1.52 mMol/l) and bicarbonate ion (22.00±1.58 mMol/l to 23.60±2.30 mMol/l). Concentration of liver function parameters followed the ranges: Total protein (57.80±3.96mg/dl to 63.33±4.16 mg/dl), Albumin (30.40±2.07 g/dl to 31.50±2.34 g/dl) and total bilirubin (7.60±0.89 g/dl to 9.20±0.84 g/dl). Concentration of lipid profile parameters ranged as follows: triglycerides (1.13±0.15 mMol/l to 1.90±0.15 mMol/l), cholesterol (3.62±0.60 mMol/l to 5.02±0.47 mMol/l), HDL-cholesterol (1.10±0.10 mMol/l to 1.34±0.21 mMol/l) and LDL-cholesterol (1.71±0.88 mMol/l to 3.04±0.33 mMol/l). The compounded diets may have minimal toxic effects on the liver and kidney as can be seen from the results of the kidney and liver function tests however consumption of these mollusk samples may tend to predispose consumers to obesity and high blood cholesterol especially E. radiata.
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