Assessment of substituent effects on β-naphthyl based isoxazoles by IR and NMR spectra

ABSTRACT
A series containing thirteen 3-(2-naphthyl)-5-(substituted phenyl)-4,5-dihydroisoxazole have
been synthesized and examined their purities by their data reported earlier. The characteristic infrared
νC=N (cm-1
) stretches, NMR chemical shifts (δ, ppm) of H4,4׳, H5 protons, C3-5 carbons were assigned
and correlated with Hammett substituent constants and Swain-Lupton’s parameters using single and
multi- regression analysis. From the results of regression analysis the effect of substituents on the
spectral data have been studied.

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