Synthesis of some Novel Halogenated Platinum (II) Complexes of Active Schiff’s Base Ligand Derived from 5-Bromo Isatin and Evaluation of their Antibacterial Activity

ABSTRACT
This paper presents the synthesis and antibacterial studies some novel halogenated Platinum (II)
complexes of active Schiff’s base ligands of the type [Pt(L1H)2]Cl2, [Pt(L2H)2]Cl2 and[Pt(L)2] derived
from 5-Bromo Isatin. Where L1H= hydrazinecarbothiamide of 5-bromoindolinedione and L2H =
hydrazinecarboxamide of 5-bromoindolinedione. All complexes reported here had been characterised
by 1H NMR and IR spectral studies. Molar conductance studies support the 1:2 natures of these
complexes. Pt (II) complexes are diamagnetic in nature and showing square planner geometry. The IR
spectral data reveals that both the Schiff’s bases (L1H and L2H) behave as bidentate ligands and are
co-ordinated to Pt (II) metal through the sulfur and hydrogenic nitrogen atom.all the new synthesized
compounds were screened for antibacterial activity against four of the test organisms like Bacillus
pumilus, Micrococcus Lutes, E. coli and Salmonella abony

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WSN 10 (2015) 32-43