ABSTRACT
Six Cu(II) mixed-ligand complexes were synthesized using 5-hydroxy-8,9-dihydrobenzo[f]indeno[5,4-c]chromen-4(7H)-one (L) and quinazolinone Schiff bases (B1-B6). These complexes were fully characterized through various techniques, including elemental analysis, infrared (IR) spectroscopy, proton nuclear magnetic resonance (1H-NMR) spectroscopy, fast atom bombardment mass spectrometry (FAB-MS), magnetic measurement, and thermal analysis. Furthermore, the biological activities of these ligands, complexes, and metal salt were evaluated against microorganisms and compared with standard drugs. The results revealed that the newly formed metal complexes exhibited significantly elevated biological activities compared to the free ligands and metal salt. These findings suggest the potential of these mixed-ligand complexes for further advancement as antimicrobial agents.
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